Remote and Anesthetic-Induced Myocardial Preconditioning Is Preserved in Atherosclerotic LDL Receptor-/- Mice In Vivo

Figure 2

Atherosclerotic vs. normal aortic root. Cross-section and HE staining of mouse aortic root (40-fold magnification). (a) Aortic root of a C57/BL 6 LDLR-/- mouse after 14 weeks of high-fat/atherogenic diet. (b) Aortic root of a C57/BL 6 WT mouse without a high-fat diet. (a) Typical criteria for severe arteriosclerosis can be seen. Significant increase of the aortic wall thickness (black line) compared to the WT aorta in (b). Also further typical atherosclerotic morphological changes can be identified: plaque cap (black arrow), foam cells, and cholesterol crystals (white arrow).