Serum PCSK9 Correlates with PTX3 and Apolipoproteins B, A1, and C3 Concentrations in Patients with Type 2 Diabetes

Table 4

Regression and partial correlation coefficients between examined variables and PCSK9 in patients with type 2 diabetes mellitus, after adjustment for age and sex.

Parameter
	Diabetes duration (yrs)	114	-1.019	-0.07	0.13	0.4594
HbA1c (%)	87	-9.608	-0.21	0.03	0.0533
Waist circumference (cm)	113	0.923	0.12	0.04	0.2125
WHR	112	94.642	0.06	0.37	0.5557
BMI (kg/m^2)	116	2.705	0.15	0.04	0.1061
SBP (mmHg)	115	1.028	0.17	0.15	0.0674
DBP (mmHg)	115	1.781	0.20	0.03	0.0342
TC (mmol/l)	106	43.398	0.56	0.07	<0.001
TG (mmol/l)	106	35.796	0.43	0.05	<0.001
HDL-C (mmol/l)	106	14.826	0.04	0.06	0.6688
LDL-C (mmol/l)	98	38.147	0.45	0.08	<0.001
Glucose (mmol/l)	91	0.687	0.02	0.01	0.8747
Creatinine (mmol/l)	108	0.302	0.07	0.15	0.4685
Uric acid (μmol/l)	103	0.173	0.16	0.05	0.1217
Bilirubin (μg/dl)	95	-1.814	-0.08	0.06	0.4235
CK-18 (U/l)	116	0.011	0.06	0.10	0.5384
PTX3 (ng/ml)	116	16.033	0.46	0.05	<0.001
apo B48 (ng/ml)	115	0.008	0.31	0.02	0.0008
apo B100 (mg/dl)	116	1.681	0.43	0.01	<0.001
apo A1 (mg/dl)	116	1.623	0.46	0.00	<0.001
apo C3 (μg/dl)	115	0.260	0.30	0.06	0.0013
sLDLr (ng/ml)	116	-2.478	-0.79	0.04	<0.001
FLI	100	0.751	0.16	0.03	0.1179
AST (U/l)	109	-0.153	-0.04	0.11	0.6539
ALT (U/l)	110	-0.202	-0.07	0.17	0.4601
GGTP (U/l)	106	-0.033	-0.01	0.10	0.9027

: partial regression coefficient; : partial correlation coefficient; : partial determination coefficient.