Research Article
Impact of Thrombocytopenia on In-Hospital Outcome in Patients Undergoing Percutaneous Coronary Intervention
Table 2
The association between thrombocytopenia and the occurrence of clinical outcomes.
| Clinical outcomes | With TCP () | Without TCP () | value | Adjusted odds ratio (95% CI)$ | value | (%) |
| Primary outcome: all-cause mortality, bleeding, or transfusion | 37 (4.0) | 215 (2.5) | 0.009 | 1.30 (0.88–1.93) | 0.19 | All-cause mortality | 16 (1.7) | 93 (1.1) | 0.09 | 1.23 (0.67–2.25) | 0.50 | Bleeding | 14 (1.5) | 85 (1.0) | 0.15 | | | | 12 (1.3) | 51 (0.6) | 0.014 | 1.90 (0.98–3.68) | 0.06 | BARC 1 | 2 (0.2) | 34 (0.4) | | | | BARC 2 | 6 (0.6) | 21 (0.2) | | | | BARC 3a | 4 (0.4) | 16 (0.2) | | | | BARC 3b | 1 (0.1) | 9 (0.1) | | | | BARC 3c | 0 (0) | 3 (0) | | | | BARC 5a | 1 (0.1) | 2 (0) | | | | Transfusion | 18 (1.9) | 90 (1.0) | 0.016 | 1.53 (0.88–2.66) | 0.13 | RBC transfusion | 16 (1.7) | 79 (0.9) | 0.021 | 1.52 (0.85–2.72) | 0.16 | Platelet transfusion | 1 (0.1) | 4 (0.05) | 0.99 | | | Plasma transfusion | 4 (0.4) | 18 (0.2) | 0.34 | | | Secondary outcome: MACE or CVA | 28 (3.0) | 212 (2.5) | 0.33 | 1.03 (0.68–1.57) | 0.89 | MACE | 19 (2.0) | 123 (1.4) | 0.15 | 1.14 (0.67–1.94) | 0.63 | Cardiac mortality | 13 (1.4) | 85 (1.0) | 0.25 | 1.08 (0.56–2.06) | 0.82 | Myocardial infarction | 3 (0.3) | 29 (0.3) | 1.0 | | | Target vessel revascularization | 3 (0.3) | 5 (0.1) | 0.042 | 4.93 (1.13–21.46) | 0.03 | Stent thrombosis | 0 (0) | 8 (0.1) | 1.0 | | | Ischemic CVA | 9 (1.0) | 93 (1.1) | 0.73 | 0.83 (0.41–1.65) | 0.59 | Hemorrhagic CVA | 0 (0) | 3 (0) | 1.0 | | | Length of stay (days) | 5 (3–7) | 4 (3–6) | 0.007 | 0.01 (-0.01–0.02)& | 0.52 |
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PCI: percutaneous coronary intervention; TCP: thrombocytopenia; CI: confidence interval; BARC: Bleeding Academic Research Consortium; RBC: red blood cell; MACE: major adverse cardiovascular events, including in-hospital cardiac mortality, myocardial infarction, target vessel revascularization, or stent thrombosis; CVA: cerebrovascular accident. $Adjusted for the propensity score in regression models. & coefficient (95% CI) of lg10-transformed length of stay. |