Research Article

Impact of Thrombocytopenia on In-Hospital Outcome in Patients Undergoing Percutaneous Coronary Intervention

Table 2

The association between thrombocytopenia and the occurrence of clinical outcomes.

Clinical outcomesWith TCP ()Without TCP () valueAdjusted odds ratio (95% CI)$ value
(%)

Primary outcome: all-cause mortality, bleeding, or transfusion37 (4.0)215 (2.5)0.0091.30 (0.88–1.93)0.19
All-cause mortality16 (1.7)93 (1.1)0.091.23 (0.67–2.25)0.50
Bleeding14 (1.5)85 (1.0)0.15
12 (1.3)51 (0.6)0.0141.90 (0.98–3.68)0.06
BARC 12 (0.2)34 (0.4)
BARC 26 (0.6)21 (0.2)
BARC 3a4 (0.4)16 (0.2)
BARC 3b1 (0.1)9 (0.1)
BARC 3c0 (0)3 (0)
BARC 5a1 (0.1)2 (0)
Transfusion18 (1.9)90 (1.0)0.0161.53 (0.88–2.66)0.13
RBC transfusion16 (1.7)79 (0.9)0.0211.52 (0.85–2.72)0.16
Platelet transfusion1 (0.1)4 (0.05)0.99
Plasma transfusion4 (0.4)18 (0.2)0.34
Secondary outcome: MACE or CVA28 (3.0)212 (2.5)0.331.03 (0.68–1.57)0.89
MACE19 (2.0)123 (1.4)0.151.14 (0.67–1.94)0.63
Cardiac mortality13 (1.4)85 (1.0)0.251.08 (0.56–2.06)0.82
Myocardial infarction3 (0.3)29 (0.3)1.0
Target vessel revascularization3 (0.3)5 (0.1)0.0424.93 (1.13–21.46)0.03
Stent thrombosis0 (0)8 (0.1)1.0
Ischemic CVA9 (1.0)93 (1.1)0.730.83 (0.41–1.65)0.59
Hemorrhagic CVA0 (0)3 (0)1.0
Length of stay (days)5 (3–7)4 (3–6)0.0070.01 (-0.01–0.02)&0.52

PCI: percutaneous coronary intervention; TCP: thrombocytopenia; CI: confidence interval; BARC: Bleeding Academic Research Consortium; RBC: red blood cell; MACE: major adverse cardiovascular events, including in-hospital cardiac mortality, myocardial infarction, target vessel revascularization, or stent thrombosis; CVA: cerebrovascular accident. $Adjusted for the propensity score in regression models. & coefficient (95% CI) of lg10-transformed length of stay.