Review Article

Rivaroxaban: Expanded Role in Cardiovascular Disease Management—A Literature Review

Table 1

Indications and approval of rivaroxaban.

IndicationYear of approvalCountry

DVT/PE prophylaxis in hip and knee surgery2008 in Europe
2011 in USA
Atrial fibrillation2011USA and Europe
DVT/PE treatment2012USA and Europe
Acute coronary syndrome2013Europe
To reduce risk of VTE after 6 months of treatment of DVT/PE2017USA and Europe
Stable CAD2018USA and Europe
PAD2018USA and Europe
DVT/PE prophylaxis in acute medical illness2019USA

DVT/PE: deep vein thrombosis/pulmonary embolism; CAD: coronary artery disease; PAD: peripheral arterial disease.