Cardioprotective Effect of Nec-1 in Rats Subjected to MI/R: Downregulation of Autophagy-Like Cell Death

Figure 3

Assessment of cardiac function in vehicle and Nec-1-treated rats at different time points (12 h, 24 h, 48 h, and 72 h) during MI/R: (a) LVDP; (b) LVEDP; (c) −dp/dtmax; (d) +dp/dtmax in different groups. mice for baseline; for vehicle group: I30min , R12h , R24h , R48h , R72h ; for Nec-1 group: I30min , R12h , R24h , R48h , R72h . All data were expressed as . ^##, baseline vs. vehicle group (I30 min). or , Nec-1 group vs. vehicle group (I30min/R12h, 24 h, 48 h, 72 h).

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