Cardiovascular Therapeutics

Research Article

Comparison between High-Power Short-Duration and Conventional Ablation Strategy in Atrial Fibrillation: An Updated Meta-Analysis

Table 2

Ablation settings of included studies.

(a)


Study ID (author, year)	Mapping system	Ablation catheter	Treatment group	Power (W)	Ablation time per point (s)	AI or LSI	Contact force setting (g)

Nilsson, 2006 [7]	LASSO	Celsius ThermoCool	HPSD		20	N/A	N/A
			LPLD		120
Yamada, 2006 [20]	QMS2™	Constellation	HPSD		60	N/A	N/A
			LPLD		60
Dhillon, 2019 [35]	CARTO	Thermocool STSF or ST	HPAI	30 (posterior), 40 (elsewhere)^a	N/A	AI: 350-450	10-20
			Conventional	25 (posterior), 30 (elsewhere)^a
Berte, 2019 [37]	LASSO NAV	ThermoCool STSF	HPSD-CLOSE	35 (posterior), 45 (elsewhere)^a	N/A	AI: ≥400, (posterior) ≥550 (anterior)^a	N/A
			Standard-CLOSE	25 (posterior), 35 (elsewhere)^a
Okamatsu, 2019 [27]	CARTO-3	ThermoCool STSF	HP	40 (posterior), 50 (elsewhere)^a	N/A	AI: 400 (anterior), 360 (posterior) 260 (esophagus)^a	N/A
			LP	20 (posterior), 30 (elsewhere)^a
Pambrun, 2019 [25]	CARTO-3	ThermoCool ST	HPSD	40 (posterior), 50 (elsewhere)^a		N/A	N/A
			LPLD	25 (posterior), 30 (elsewhere)^a
Vassallo, 2019 [22]	Ensite velocity 4.0 or 5.0	TactiCath	HPSD	45 (posterior), 50 (elsewhere)^a	6	N/A	8-20
			Conventional	30	30		10-30
Castrejón-Castrejón, 2020 [36]	CARTO-3	TactiCath™ Quartz and SE, Abbott, or ThermoCool ST	HPSD	50-60	7 or <30	or (posterior) (elsewhere)^a	5-40
			Conventional	20-30	30-60	N/A	N/A
Ejima, 2020 [33]	CARTO	ThermoCool STSF	HPSD	50	3-5	N/A	5-20
			Conventional	25 (esophagus), 30-40 (elsewhere)^a	5-10		10-20
Kottmaier, 2020 [8]	N/A	Abbott flexibility SE catheter	VHPSD	70	5-7	N/A	N/A
			LPLD	30-40	20-40
Kyriakopoulou, 2020 [30]	LASSO	ThermoCool ST	HPSD	40	20-40	AI: ≥400 (posterior/roof/south pole), ≥ 550 (anterior)^a	12-15
			LPLD	35	N/A		12-15
Leo, 2020 [28]	Ensite velocity, precision or Optima	TactiCath Quartz	HPSD	20 (posterior), 40 (elsewhere)^a	N/A	LSI: 6 (anterior), 4 or 5 (posterior)^a
			LPLD	20
Shin, 2020 [23]	CARTO-3	ThermoCool STSF	HPSD	25-30 (posterior), 40 or 50 (elsewhere)^a	10 or 20	N/A	Blind to operators
			LPLD	25-30 (posterior), 30 (elsewhere)^a	40
Yavin, 2020 [19]	CARTO-3	ThermoCool STSF	HPSD	45-50	8 (posterior), 15 (elsewhere)^a	N/A	N/A
			MPLD	20 (posterior), 30-40 (elsewhere)^a	20 (posterior), 30 (elsewhere)^a

(b)


Study ID (author, year)	Mapping system	Ablation catheter	Treatment group	Power (W)	Ablation time per point (s)	AI, LSI, or FTI	Contact force (g)

Yazaki, 2020 [18]	CARTO-3	ThermoCool	HPSD	50	8-12	N/A	5-15
			LPLD	20-25 (posterior), 25-40 (elsewhere)^a	30		10-20
Dikdan, 2021 [34]	St. Jude EnSite Velocity system	ThermoCool	HPSD	50	15	LSI: 5 (posterior) 6 (elsewhere)^a	8-40
			SPSD	20-25	30-60	LSI: 4.5–5.5	10-40
Wielandts, 2021 [21]	N/A	ThermoCool ST	HP-CLOSE	45	N/A	AI: ≥550 (anterior), ≥400 (elsewhere)^a	≤30
			LP-CLOSE	35
Francke, 2021 [32]	Carto 3	ThermoCool STSF	HP-CLOSE	50	N/A	AI: 400 (posterior) and 550 (anterior)^a	N/A
			Standard-CLOSE	20 (posterior), 40 (elsewhere)^a
Hansom, 2021 [31]	Carto 3, PentaRay, or Lasso	ThermoCool	HPSD	50	6-8 (posterior)^a 8-10 (elsewhere)^a	N/A	10-20
			FTI-guided LDLD	20 (posterior), 30 (elsewhere)^a	Determined by LSI, typically 20-25 (posterior) 30-40 (elsewhere)^a	g·s (posterior)^a g·s (elsewhere)^a
Richard, 2021 [24]	Carto 3	QDOT Microcatheter	VHPSD	90	4	N/A	N/A
			Conventional	25-40	N/A	AI: 550 (anterior), 450 (roof), 380 (posterior)^a	10-40
Lee, 2021 [29]	Carto 3	ThermoCool STSF	HPAI	25, 30-40	N/A	AI: ≥450 (anterior/roof), ≥350 (posterior/inferior/carina)^a	5-20
		ThermoCool ST	CPAI	25-35
Okamatsu, 2019 [27]	Carto 3	ThermoCool STSF	HP	25, 40-50	N/A	AI: ≥400 (anterior), ≥360 (posterior), ≥260 (esophagus)^a	10-20
			CP	20-40

Values are presented as . ^aAnterior or posterior refers to the anterior left atrial wall and posterior left atrial wall, respectively. PVI: pulmonary vein isolation; AI: ablation index; LSI: lesion size index; FTI: force-time integral; HPSD: high-power short-duration; LPLD: low-power long-duration; HPAI: high-power ablation index; CLOSE: CLOSE protocol; HP: high-power; LP: low-power; VHPSD: very-high-power short-duration; MPLD: moderate-power moderate-duration; STSF: Smart Touch Surround Flow (catheter).