Thymosin β4 Protects against Cardiac Damage and Subsequent Cardiac Fibrosis in Mice with Myocardial Infarction

<div>Tβ4 inhibits myofibroblast growth and TGF-β1-induced activation. Development of myofibroblast cells treated by Tβ4 (75-150 nM, 12 h) (a). Expression of α-SMA and vimentin in myofibroblast cells treated by Tβ4 (150 nM, 12 h) and/or TGF-β1 (5 ng/mL) at mRNA (b) and protein (c) levels.</div>

Cardiovascular Therapeutics

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Figure 8

Figure 8: Thymosin β4 Protects against Cardiac Damage and Subsequent Cardiac Fibrosis in Mice with Myocardial Infarction