Research Article
Thymosin β4 Protects against Cardiac Damage and Subsequent Cardiac Fibrosis in Mice with Myocardial Infarction
Table 2
AAV-Tβ4 alleviates increases in MDA content and MPO activity in heart tissues.
| | MDA | (nmol/mg protein) | MPO | (U/mg protein) | Day 7 | Day 42 | Day 7 | Day 42 |
| NS | 0.71 ± 0.66 (n = 7) | 0.82 ± 0.36 (n = 7) | 0.48 ± 0.42 (n = 7) | 0.66 ± 0.25 (n = 7) | AMI | 1.45 ± 0.43 (n = 7) | 1.88 ± 0.85 (n = 4) | 0.92 ± 0.23 (n = 7) | 1.27 ± 0.89 (n = 4) | AMI+AAV-LacZ | 1.48 ± 0.33 (n = 7) | 1.97 ± 0.86 (n = 5) | 0.89 ± 0.35 (n = 7) | 1.12 ± 0.93 (n = 5) | AMI+AAV-Tβ4 | 0.91 ± 0.27 (n = 7) | 1.18 ± 0.41 (n = 6) | 0.55 ± 0.12 (n = 7) | 0.78 ± 0.23 (n = 6) |
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P<0.05 vs the AMI or AMI+AAV-LacZ group. |