Thymosin β4 Protects against Cardiac Damage and Subsequent Cardiac Fibrosis in Mice with Myocardial Infarction

Table 3

AAV-Tβ4 alleviates upregulation of inflammatory factors in heart tissues.

(a)

Day 7	n	IL-1β (pg/mL)	IL-6 (pg/mL)	TNF-α (pg/mL)
NS	7	32.29 ± 2.92	34.29 ± 3.29	3.87 ± 0.38
AMI	7	55.86 ± 5.16	59.29 ± 5.17	6.36 ± 0.50
AMI+AAV-LacZ	7	51.57 ± 5.69	58.71 ± 5.58	6.41 ± 0.56
AMI+AAV-Tβ4	7	38.71 ± 4.02	40.71 ± 3.90	3.39 ± 0.41

(b)

Day 42	n	IL-1β (pg/mL)	IL-6 (pg/mL)	TNF-α (pg/mL)
NS	7	64.32 ± 3.24	75.56 ± 2.45	7.02 ± 2.21
AMI	4	89.41 ± 3.98	95.43 ± 4.48	18.76 ± 1.96
AMI+AAV-LacZ	5	90.13 ± 4.65	89.33 ± 3.32	16.53 ± 3.94
AMI+AAV-Tβ4	6	66.41 ± 5.54	78.89 ± 3.76	9.09 ± 1.97

P<0.01 vs the AMI or AMI+AAV-LacZ group.