Research Article

Positive Association of Plasma Trimethylamine-N-Oxide and Atherosclerosis in Patient with Acute Coronary Syndrome

Table 1

Baseline characteristics of patients.

MetricMild
()
Moderate
()
Severe
()

Age, M (P25, P75)59 (54, 67)64 (55, 71)60 (52, 70)0.669
Gender (male), (%)9 (69.2)26 (78.8)57 (70.4)0.635
Smoking, (%)7 (53.8)19 (57.6)46 (56.8)0.974
Hypertension, (%)7 (53.8)25 (75.8)44 (54.3)0.095
Diabetes mellitus, (%)3 (23.1)13 (39.4)24 (29.6)0.470
ACS0.577
 STEMI, (%)6 (46.2)14 (42.4)38 (46.9)
 NSTEMI, (%)1 (7.7)6 (18.2)19 (23.5)
 UA, (%)6 (46.2)13 (39.4)24 (29.6)
The ST changes of the ECG were observed0.377
 No change, (%)6 (46.2)10 (30.3)19 (23.5)
 Elevation, (%)6 (46.2)14 (42.4)40 (49.4)
 Shift down, (%)1 (7.7)9 (27.3)22 (27.2)
Gensini score, M (P25, P75)18 (16, 24)40 (37, 45)68 (59, 81)<0.001
BMI, M (P25, P75)26.1 (25.1, 26.4)25.2 (24.7, 26.2)24.8 (23.8, 26.4)0.262
TNI, M (P25, P75)0.32 (0.02, 13.03)0.33 (0.02, 8.36)0.20 (0.02, 5.23)0.981
BNP, M (P25, P75)139.80 (28.18, 207.62)111.00 (81.61, 250.87)84.04 (50.39, 200.65)0.142
CK-MB, M (P25, P75)18.32 (14.65, 42.60)52.10 (19.00, 206.83)29.50 (17.30, 91.75)0.079
CK, M (P25, P75)124.85 (98.08, 446.30)376.60 (118.45, 1576.73)204.50 (88.40, 844.60)0.087
HBDH, M (P25, P75)213.45 (143.63, 451.85)268.90 (164.98, 688.20)204.05 (146.63, 418.38)0.333
LDH, M (P25, P75)414.00 (203.60, 570.53)398.40 (202.83, 957.53)315.90 (198.95, 626.06)0.793
CHOL, M (P25, P75)4.85 (4.10, 5.55)5.18 (4.08, 6.36)5.03 (4.13, 5.81)0.846
LDL-CD, M (P25, P75)3.32 (2.54, 3.95)3.70 (2.57, 4.41)3.57 (2.69, 4.22)0.832
TG, M (P25, P75)1.35 (0.96, 2.02)1.57 (1.01, 2.25)1.41 (1.04, 2.00)0.850
Cr, M (P25, P75)83.10 (63.80, 100.30)84.80 (69.00, 107.70)79.20 (65.95, 96.75)0.604
IMT, M (P25, P75)11.70 (6.70, 16.25)11.80 (8.65, 14.50)10.00 (8.80, 14.10)0.814
ET-1, M (P25, P75)0.52 (0.37, 1.04)0.40 (0.27, 0.60)0.40 (0.28, 0.70)0.262
IL-8, M (P25, P75)4.78 (3.38, 9.47)3.38 (1.54, 6.53)3.38 (1.54, 7.29)0.222
NO, M (P25, P75)2.63 (1.18, 6.08)2.02 (0.52, 3.78)3.14 (1.23, 6.12)0.071
TMAO, M (P25, P75)0.79 (0.20, 1.29)1.13 (0.63, 3.34)4.73 (3.13, 6.42)<0.001