Development and Validation of a Nomogram Model for Predicting the Risk of Readmission in Patients with Heart Failure with Reduced Ejection Fraction within 1 Year

Table 2

Univariate and multivariate logistic analysis for the readmission within 1 year.

Variables	Univariate analysis OR (95% CI)	value	Multivariate analysis OR (95% CI)	value
Age (years)	1.025 (1.013,1.037)	<0.001	1.033 (1.018,1.049)	<0.001
NYHA class (, %)		0.048		0.369
II	1.000		1.000
III	1.709 (1.027,2.845)		1.355 (0.756,2.427)
IV	2.091 (1.154,3.788)		1.646 (0.824,3.287)
BMI (kg/m^2)	0.787 (0.715,0.867)	<0.001	0.783 (0.699,0.876)	<0.001
SBP (mmHg)		<0.001		<0.001
<120	1.000		1.000
>140	0.615 (0.402,0.942)		0.716 (0.430,1.194)
120–140	0.225 (0.152,0.333)		0.197 (0.194,0.479)
Comorbidities (, %)
Diabetes	2.989 (2.103,4.247)	<0.001	3.302 (2.182,4.996)	<0.001
Coronary heart disease	1.430 (1.028,1.991)	0.034	1.278 (0.856,1.908)	0.230
Anemia	1.402 (1.004,1.959)	0.048	1.487 (0.994,2.223)	0.053
eGFR (mL/min)	0.994 (0.988,0.999)	0.029	1.001 (0.993,1.008)	0.810
Uric acid (μmol/L)	1.001 (1.000,1.002)	0.033	1.001 (1.000,1.002)	0.093
NT-BNP (pg/mL)	1.000 (1.000,1.000)	0.181
LVEF (%)	0.925 (0.896,0.955)	<0.001	0.901 (0.867,0.937)	<0.001
Medication at admission (, %)
ARNI	0.290 (0.208,0.405)	<0.001	0.254 (0.172,0.375)	<0.001

BMI: body mass index; SBP: systolic blood pressure; eGFR: estimated glomerular filtration rate; NT-proBNP: N-terminal-pro brain natriuretic peptide; LVEF: left ventricular ejection fraction; ARNI: angiotensin receptor neprilysin inhibitors.