Research Article
Retrospective Study of Aging and Sex-Specific Risk Factors of COVID-19 with Hypertension in China
Table 2
Clinical characteristics and laboratory findings in different age of hypertensive and non-hypertensive COVID-19 patients.
| | Characteristics | Total | Elderly (> 60 yr) | Non- elderly
(≤60 yr) | value |
| | Patients with hypertension | () | () | () | | | Disease severity | | | | | | Mild | 16 (17.58%) | 2 (11.76%) | 14 (18.92%) | 0.050 | | General | 68 (74.73%) | 11 (64.71%) | 57 (77.03%) | | | Severe | 7 (7.69%) | 4 (23.53%) | 3 (4.05%) | | | Laboratory findings | | | | | | Triglycerides, mmol/L | 1.21 (0.81–2.01) | 1.50 (1.01–2.17) | 0.79 (0.71–1.00) | 0.005 | | Total bilirubin, umol/L | 12.30 (8.86–16.95) | 13.25 (9.54–17.28) | 6.00 (4.74–11.65) | 0.006 | | Indirect bilirubin, umol/L | 8.00 (5.12–12.38) | 8.50 (5.63–13.00) | 6.90 (4.90–10.95) | 0.009 | | < 1.7 | 64 (70.33%) | 13 (76.47%) | 51 (68.92%) | 0.024 | | P <0.8, mmol/L | 6 (6.60%) | 2 (11.76%) | 5 (6.76%) | 0.028 | | Ca, mmol/L | 2.23 (2.10–2.35) | 2.07 (1.94–2.22) | 2.25 (2.13–2.36) | 0.013 | | Thrombin time> 16, s | 17 (18.68%) | 0 (0%) | 17 (22.97%) | 0.022 | | D-dimer, ug/ml | 0.38 (0.20–0.79) | 0.44 (0.28–1.36) | 0.32 (0.19–0.57) | 0.030 | | Red blood cell distribution width SD, fL | 40.10 (38.50-41.75) | 41.45 (39.43-47.20) | 40.10 (36.80-41.00) | 0.007 | | Red blood cell distribution width CV, % | 12.30 (12.00-13.20) | 12.95 (12.23-14.10) | 12.20 (11.95-12.95) | 0.035 |
| | Patients without hypertension | () | () | () | | | Disease severity | | | | | | Mild | 51 (11.28%) | 6 (7.32%) | 45 (12.16%) | 0.001 | | General | 355 (78.54%) | 58 (70.73%) | 297 (80.27%) | | | Severe | 46 (10.18%) | 18 (21.95%) | 28 (7.57%) | | | Laboratory findings | | | | | | Cholinesterase, IU/L | 7454.00 (6121.25–8546.75) | 7488.00 (5682.25–9250.25) | 7435.00 (6256.25–8523.50) | 0.018 | | Lactate dehydrogenase, IU/L | 189.00 (156.67–233.10) | 188.00 (146.50–220.46) | 194.00(159.17–240.75) | 0.016 | | Indirect bilirubin<1.7, umol/L | 324 (71.68%) | 56 (68.29%) | 278 (75.14%) | 0.005 | | α-L-fucosidase, U/L | 26.00 (21.80-30.88) | 28.00 (25.88-33.85) | 25.00 (21.00-30.00) | 0.032 | | α-Hydroxybutyrate dehydrogenase, IU/L | 160.00 (137.28–197.96) | 150.50 (122.0–180.22) | 165.00(136.00–212.43) | 0.01 | | Low-density lipoprotein, mmol/L | 2.40 (1.99–3.01) | 2.81 (2.20–3.37) | 2.14 (2.08–2.28) | 0.041 | | Total cholesterol, mmol/L | 4.13 (3.59–4.85) | 4.43 (3.83–5.08) | 4.05 (3.53–4.79) | 0.038 | | Complement C1q, mg/L | 150.05 (140.14–166.21) | 134.51 (125.51–136.09) | 164.41(144.57–169.65) | 0.028 |
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