Research Article

Retrospective Study of Aging and Sex-Specific Risk Factors of COVID-19 with Hypertension in China

Table 3

Clinical characteristics and laboratory findings in different gender of hypertensive and non-hypertensive COVID-19 patients.

CharacteristicsTotalMaleFemale value

Patients with hypertension()()()
Disease severity
 Mild16 (17.58%)3 (5.88%)13 (32.50%)0.06
 General68 (74.73%)46 (90.20%)22 (55.00%)
 Severe7 (7.69%)2 (3.92%)5 (12.50%)
Symptoms
 Fever39 (42.86%)27 (52.94%)12 (30.00%)0.04
Laboratory findings
 Hematocrit, %35.15 (13.34–42.78)38.48 (17.01–50.67)34.42 (5.11–45.67)0.032
 Total bile acid, umol/L3.65 (2.30–7.23)2.75 (1.58–5.13)5.30 (3.05–7.98)0.004
 Total protein, g/L66.40 (31.00–72.23)68.20 (63.70–75.20)62.90 (58.00–70.20)0.005
   < 6014 (15.38%)4 (7.84%)10 (25.00%)0.029
 Globulin, g/L27.00 (24.30–30.45)28.30 (25.59–31.50)26.00 (22.00–28.61)0.011
 Glucose, mmol/L5.62 (4.79–7.30)6.00 (4.85–8.47)5.04 (4.67–6.20)0.021
 Cl, mmol/L102.05 (99.65–105.00)101.10 (99.06–103.85)103.16 (100.39–105.28)0.033
 Fibrinogen, g/L3.31 (2.68–4.03)3.40 (2.97–4.55)2.69 (2.29–3.54)0.018

Patients without hypertension()()()
Laboratory findings
 5‘nuclease, U/L3.00 (2.25–6.40)3.03 (2.17–6.72)4.20 (3.00–7.60)0.044
 Total bilirubin<5.13, umol/L43 (9.51%)14 (6.22%)28 (12.33%)0.038
 Urea<3.2, mmol/L94 (20.80%)39 (17.33%)55 (24.23%)0.011
 Cystatin C, mg/L1.00 (0.33–1.21)1.10 (0.37–1.30)0.97 (0.29–1.15)0.010
 Urea/creatinine66.26 (47.20–78.86)52.68 (24.97–69.79)75.10 (53.24–96.09)0.021
 Glomerular filtration rate110.31 (101.15–121.21)106.53 (99.33–122.52)115.70 (101.14–127.63)0.010
 Eosinophil count, ×109 per L
   < 0.05182 (40.27%)82 (36.44%)100 (44.05%)0.037
  0.05–0.3155 (34.29%)86 (38.22%)69 (30.40%)
   > 0.33 (0.66%)0 (0%)3 (1.32%)
 Creatinine, umol/L62.00 (52.28–75.00)66.85 (56.49–78.00)61.81 (51.95–75.00)<0.001
   < 5398 (21.68%)33 (14.67%)65 (28.63%)<0.001
  53–97266 (58.85%)142 (63.11%)124 (54.63%)
   > 9719 (4.20%)11 (4.89%)5 (2.20%)
 Red blood cell distribution width SD, fL
   < 359 (1.99%)8 (3.56%)1 (0.44%)0.011
  35–56325 (71.90%)158 (70.22%)167 (73.57%)
   > 5610 (2.21%)2 (8.89%)8 (3.52%)