Vascular Closure Devices versus Manual Compression in Cardiac Interventional Procedures: Systematic Review and Meta-Analysis

Table 1

Summary of included studies.

Study	Publication year	Research country	Study type	Operation type	Access site	VCD type	Sample size	Age ()	Male gender; (%)
Ben-Dor [28]	2018	USA	RCT	PCI/CAG	Femoral vein	MynxGrip	208		117 (56.3)
Ben-Dor [40]	2011	USA	Retrospective study	BAV	Femoral artery	AngioSeal/Perclose/Prostar	333		146 (43.8)
Bhat [41]	2021	India	Retrospective study	PCI	Femoral artery	Perclose	1743		1097 (62.9)
Christ [42]	2015	Germany	Retrospective study	PCI/CAG	Femoral artery	AngioSeal	76	64.2 ± 12.8	46 (60.5)
De Poli [43]	2014	France	Retrospective study	PCI/CAG	Femoral artery	FemoSeal	211		76 (76.0)
De Poli past [43]	2014	France	Retrospective study	PCI/CAG	Femoral artery	Unknown	3826	Unknown	Unknown
Hermiller [29]	2005	USA	RCT	CAG	Femoral artery	Starclose	208		139 (66.8)
Hermiller [30]	2006	USA	RCT	PCI	Femoral artery	Starclose	275		221 (80.4)
Hermiller [31]	2015	USA	RCT	CC	Femoral artery	Vascade	420		298 (71.0)
Holm [32]	2014	Denmark	RCT	CAG	Femoral artery	FemoSeal	1001		621 (62.0)
Iqtidar [56]	2011	USA	Propensity match	PCI	Femoral artery	AngioSeal/Starclose/Perclose	4221		2076 (64.1)
Jakobsen [33]	2022	Denmark	RCT	CAG	Femoral artery	MynxGrip	865		570 (65.9)
Junquera [57]	2021	Canada	Propensity match	TAVR	Femoral artery	AngioSeal/Perclose	4031		1921 (47.7)
Kuno [58]	2021	USA	Propensity match	PCI	Femoral artery	AngioSeal/Perclose	694		529 (76.2)
Leclercq [44]	2015	France	Prospective study	BAV	Femoral artery	AngioSeal	180		84 (46.7)
Lupi [45]	2012	Italy	Retrospective study	PCI/CAG	Femoral artery	AngioSeal	1913	Unknown	Unknown
Mirza [46]	2014	USA	Retrospective study	CC	Brachial artery	Starclose	148		79 (53.4)
Mohammed [47]	2021	USA	Prospective study	CA	Femoral vein	Perclose	231		145 (62.8)
Mohanty [48]	2019	USA	Retrospective study	CA/LAAC	Femoral vein	Vascade	803		538 (70.0)
Natale [34]	2020	USA	RCT	CA	Femoral vein	Vascade	204		131 (64.2)
O’Neill [49]	2013	USA	Retrospective study	BAV	Femoral artery	Perclose	428		194 (45.3)
Owens [50]	2017	USA	Retrospective study	CC	Femoral artery	Cardiva catalyst II	1470		1419 (96.5)
Pieper [51]	2016	Germany	Prospective study	CC	Femoral artery	ExoSeal	48		29 (60.4)
Schulz-Schüpke [ 35]	2014	Germany	RCT	CAG	Femoral artery	FemoSeal/ExoSeal	4524		3129 (69.2)
Sekhar [52]	2016	USA	Prospective study	CC	Femoral artery	Perclose	170		149 (87.6)
Sharma [36]	2020	USA	RCT	CC	Femoral artery	SiteSeal	39		23 (59.0)
Stegemann [53]	2011	Germany	Retrospective study	PCI/CAG	Femoral artery	AngioSeal	4653		3233 (69.5)
Su [54]	2018	China	Retrospective study	PCI	Femoral artery	AngioSeal	73		52 (71.2)
Wei [55]	2020	China	Retrospective study	TBAD	Brachial artery	ExoSeal	157		124 (79.0)
Wong [37]	2017	USA	RCT	PCI	Femoral artery	Celt ACD	207		159 (76.8)
Wong [38]	2009	USA	RCT	PCI/CAG	Femoral artery	ExoSeal	401		265 (66.1)
Yeni [39]	2016	Germany	RCT	PCI	Femoral artery	AngioSeal/Starclose	620		444 (71.6)

VCD = vascular closure device; USA = the United States of America; RCT = randomized controlled trial; PCI = percutaneous coronary intervention; CAG = coronary angiography; BAV = balloon aortic valvuloplasty; CC = cardiac catheterization; TAVR = transcatheter aortic valve replacement; CA = catheter ablation; LAAC = left atrial appendage closure; TBAD = type B aortic dissection.