Research Article
Bioinformatics and System Biological Approaches for the Identification of Genetic Risk Factors in the Progression of Cardiovascular Disease
Table 3
The 10 most significant hub proteins.
| Protein | Description | Associated risk factor |
| FPR2 | Formyl peptide receptor 2 | Upregulated for HTN | TNF | Tumor necrosis factor | Upregulated for HTN | CXCL8 | C-X-C motif chemokine ligand 8 | Upregulated for aging | CXCL1 | C-X-C motif chemokine ligand 1 | Upregulated for HTN | IL1B | Interleukin 1 beta | Upregulated for HTN | VEGFA | Vascular endothelial growth factor A | Upregulated for obesity | CYBB | Cytochrome B-245 beta chain | Upregulated for aging | PTGS2 | Prostaglandin-endoperoxide synthase 2 | Upregulated for HTN | ITGAX | Integrin subunit alpha X | Upregulated for aging | CCR5 | C-C motif chemokine receptor 5 | Downregulated for HTN |
|
|