| GO ID | Pathway | Genes in pathway | Risk factors | value |
| GO:0042310 | Vasoconstriction | ADRA1A, SLC8A1 | HCL, HTN | 2.02E-02 | GO:0014829 | Vascular smooth muscle contraction | SLC8A1 | HCL | 1.9E-02 | GO:0030194 | Positive regulation of blood coagulation | THBD, TLR4, and THBS1 | Obesity, HTN | 4.71E-04 | GO:0045823 | Positive regulation of heart contraction | ADM, ADRA1A, and TGFB2 | HTN, aging, and obesity | 4.71E-04 | GO:0035051 | Cardiomyocyte differentiation | TGFB2, NRG1 | Aging | 1.64E-03 | GO:0070508 | Cholesterol import | APOA1 | Aging | 2.78E-02 | GO:0006954 | Inflammatory response | CCL20, NFAM1, TNFRSF21, MMP25, IL2RA, PTGER3, FOS, LYZ, THBS1, IL1B, CXCL1, FPR2, TNF, and TLR4 | T2D, obesity, and HTN | 6.30E-05 | GO:0045765 | Regulation of angiogenesis | TGFB2, PTGIS, THBS1, GTF2I, VEGFA, PTGIS, PRKD1, PML, IL1B, and CYP1B1 | Obesity, HCL, HTN, and obesity | 3.90E-04 | GO:0070486 | Leukocyte aggregation | IL1B | HTN | 1.18E-02 | GO:0032722 | Positive regulation of chemokine production | IL1B, TNF, and TLR4 | HTN | 2.59E-05 | GO:0043410 | Positive regulation of MAPK cascade | CCL13, TGFB2, CCL20, ACKR3, S100A12, ACKR3, FPR2, TNF, and ADRA1A | HTN, aging | 1.22E-03 |
|
|