Cardiovascular Therapeutics

Research Article

Circulating FABP-4 Levels in Patients with Atherosclerosis or Coronary Artery Disease: A Comprehensive Systematic Review and Meta-Analysis

Table 2

Baseline characteristics of the included primary studies that evaluated the FABP-4 level in patients with atherosclerosis or coronary artery disease in the present systematic review and meta-analysis.
AuthorYearCountryMethodKit typeFABP-4 commercial kit type and companyDesign case/ controlAge case (mean)Age control (mean)#FABP-4 ()SMD (Se)Secondary outcome ()
CaseControlSubgroupCaseControl
Rhee et al. [7]2009South KoreaELISASandwich ELISABioVendorCS135/990.86 (0.14)BMI
LDL
HDL
TG
TC
Miyoshi et al. [20]2010JapanELISASandwich ELISABioVendorCC125/1200.85 (0.13)BMI
LDL
HDL
TG
Jin et al. [9]2010ChinaELISASandwich ELISABioVendorCS211/1290.16 (0.11)BMI
LDL
HDL
TG
TC
Holm et al. [21]2011NorwayELISASandwich ELISABioVendorCS28/311.65 (0.3)BMI—
LDL
HDL
TC
Doi et al. [22]2011JapanELISASandwich ELISABioVendorCC211/2110.79 (0.1)BMI
LDL
HDL
TG
Bao et al. [11]2011ChinaELISASandwich ELISABioVendorCS247/94——0.05 (0.12)———
Hong et al. [23]2011ChinaELISASolid phase sandwich ELISAR&D SystemsCS238/2210.26 (0.09)BMI
LDL
HDL
TG
TC
Kajiya et al. [5]2013JapanELISASandwich ELISABioVendorCC115/500.85 (0.18)BMI
LDL
HDL
TG
Wu et al. [24]2020TaiwanELISASolid phase sandwich ELISAR&D SystemsCC22/400.19 (0.27)BMI
LDL
HDL
TG
TC
Measurement unit of fatty acid-binding proteins (FABP)-4 was Ng/ml. SMD: standardized mean difference; Se: standard error; BMI: body mass index; LDL: low-density lipoprotein; HDL: high-density lipoprotein; TG: triglyceride; TC: total cholesterol.