Use of Statin Therapy to Reduce Cardiovascular Risk in Older Patients

Table 1

Proportions of older patients enrolled in pivotal statin trials.

Study	Characteristics	Age at enrolment
		≥65 years	≥70 years
Scandinavian Simvastatin Survival Study (4S) [10]	Simavastatin versus placebo Patients aged 35–70 years; n = 4444	23%	—
Cholesterol and Recurring Events (CARE) Trial. Lewis et al. [13]	Pravastatin versus placebo Patients aged 21–75 years; n = 4059	31%	12%
Heart Protection Study (HPS) [17]	Simavastatin versus placebo Patients aged 40–80 years; n = 20 536	52%	28%
Treating to New Targets (TNT). Wenger et al. [22]	Atorvastatin 80 mg versus 10 mg Patients aged 35–75 years; n = 10 001	38%	18%