Clinical Study

A Quantitative Assessment of Tremor and Ataxia in Female FMR1 Premutation Carriers Using CATSYS

Table 1

Patient characteristics.

Controls ( 𝑁 = 3 7 )Non-FXTAS ( 𝑁 = 9 0 )FXTAS ( 𝑁 = 2 3 ) 𝑃 value

Age56.53 (7.79)52.89 (9.40)62.69 (12.27)<.0001a
Education14 (3.02)15.35 (2.91)14.66 (2.45).1692a
Ethnicity( 𝑁 c = 3 1 )( 𝑁 = 8 7 )( 𝑁 = 2 2 )
Caucasian93.5% (29)82.8% (72)100% (22)
Hispanic6.4% (2)12.6% (11)0%
Other0%4.9% (4)0%
CGG Repeat29.61 (5.65)86.66 (17.01)90.52 (31.38).3917b
FMR1 mRNA1.72 (0.75)2.51 (0.94)2.24 (0.84).2474b
AR0.54 (0.18)0.58 (0.21).3712b

aOverall ANOVA P value.
bComparison between FXTAS and non-FXTAS.
cLess than total sample sizes due to missing ethnicity data.