A Quantitative Assessment of Tremor and Ataxia in Female FMR1 Premutation Carriers Using CATSYS

Table 3

Exploratory comparison of secondary outcome CATSYS measures.

		Control (𝑁=37)		Non-FXTAS (𝑁=90)		FXTAS (𝑁=23)
CATSYS group	CATSYS performance; task	Mean	SD	Mean	SD	Mean	SD	FXTAS versus control	Non-FXTAS versus control	FXTAS versus non-FXTAS
Manual coordination, Maximum frequency (Hz)	Hand
	Dominant	7.07	0.82	6.82	0.98	6.42	1.14	*	ns^a	ns
	Nondominant	6.90	0.93	6.60	1.01	6.20	1.36	*	ns	ns
	Finger tapping
	Dominant	7.46	1.10	7.25	1.38	6.50	1.73	*	*	ns
	Nondominant	7.19	1.36	7.31	1.27	6.32	1.75	*	**	ns
Reaction; Time (sec)	Hand
	Dominant	0.24	0.05	0.24	0.05	0.27	0.05	*	ns	ns
	Nondominant	0.23	0.05	0.24	0.05	0.26	0.05	*	*	ns
Writing; Tremor,; tremor; Intensity (m/sec^2)	Hand
	Dominant	0.53	0.47	0.74	1.03	0.93	1.19	ns	ns	ns
	Nondominant	0.59	0.54	0.70	0.94	1.00	1.15	ns	ns	ns

Analysis based on logarithm transformed data and adjusted for age.
^a Not significant (𝑃>.10).
** 𝑃<.01.
* 𝑃<.05.