Identification of Neuroprotective Factors Associated with Successful Ageing and Risk of Cognitive Impairment among Malaysia Older Adults

Table 3

Determination of significant neuroprotective factors associated with risk of cognitive impairment.

	Selected neuroprotective factors			95% confidence interval
				Upper	Lower
MCI	Serum Vitamin D (nmol/L)	−0.05	0.96	0.92	0.99	<0.0
	Telomere Length (kb/diploid genome)	−0.03	0.97	0.95	0.99	<0.00
	BDNF (nmol/L)	−0.67	0.51	0.30	0.88	<0.0
UA	Serum Vitamin D (nmol/L)	−0.02	0.98	0.94	1.02	>0.05
	Telomere Length (kb/diploid genome)	−0.03	0.98	0.96	0.99	<0.0
	BDNF (nmol/L)	−0.59	0.56	0.33	0.93	<0.0

BDNF: brain-derived neurotrophic factor; SA: successful ageing; UA: usual ageing; MCI: mild cognitive impairment. Multinomial Logistic Regression with reference group is successful ageing. ignificant at after being controlled for age, gender, educational level, and smoking status. ignificant at after being controlled for confounding factors: age, gender, educational level, smoking, physical function, and depressive symptoms.