Research Article
Diseases Linked to Polypharmacy in Elderly Patients
Table 2
Comparison of medical history between patients in polypharmacy and nonpolypharmacy group.
| | Medical history | Polypharmacy group
(53.5%) | Nonpolypharmacy group
(46.5%) | Statistical significance |
| | Morbidity | | | | | Arterial hypertension | | | | | Yes | 125 (75.3%) | 79 (54.9%) | | | No | 41 (24.7%) | 65 (45.1%) | ( = 14.317) | | Hyperlipidemia/dyslipidemia | | | | | Yes | 49 (29.5%) | 20 (13.9%) | | | No | 117 (70.5%) | 124 (86.1%) | ( = 10.885) | | Diabetes mellitus | | | | | Yes | 72 (43.4%) | 30 (20.8%) | | | No | 94 (56.6%) | 114 (79.2%) | ( = 17.745) | | Stroke | | | | | Yes | 21 (12.7%) | 5 (3.5%) | | | No | 145 (87.3%) | 139 (96.5%) | ( = 8.454) | | Heart failure | | | | | Yes | 31 (18.7%) | 4 (2.8%) | | | No | 135 (81.3%) | 140 (97.2%) | ( = 19.456) | | Atrial fibrillation | | | | | Yes | 54 (32.5%) | 13 (9.0%) | | | No | 112 (67.5%) | 131 (91.0%) | ( = 25.140) | | Coronary artery disease | | | | | Yes | 51 (30.7%) | 7 (4.9%) | | | No | 115 (69.3%) | 137 (95.1%) | ( = 33.909) | | Chronic renal failure | | | | | Yes | 9 (5.4%) | 1 (0.7%) | | | No | 157 (94.6%) | 143 (99.3%) | ( = 5.520) | | COPD | | | | | Yes | 23 (13.9%) | 7 (4.9%) | | | No | 143 (86.1%) | 137 (95.1%) | ( = 7.137) | | Dementia | | | | | Yes | 31 (18.7%) | 11 (7.6%) | | | No | 135 (81.3%) | 133 (92.4%) | ( = 8.018) | | Benign prostate hyperplasia | | | | | Yes | 14 (8.4%) | 4 (2.8%) | | | No | 152 (91.6%) | 140 (97.2%) | ( = 4.510) | | Thyroid diseases | | | | | Yes | 24 (14.5%) | 9 (6.3%) | | | No | 142 (85.5%) | 135 (93.8%) | ( = 5.461) | | Hyperuricemia | | | | | Yes | 19 (11.4%) | 4 (2.8%) | | | No | 147 (88.6%) | 140 (97.2%) | ( = 8.435) |
| | CCI (95% CI) | 5.77 (5.54–5.99) | 5.13 (4.79–5.50) |
( = 7798.000) |
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COPD: chronic obstructive pulmonary disease; CCI: Charlson Comorbidity Index; CI: confidence interval.
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