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Current Gerontology and Geriatrics Research
Volume 2018, Article ID 9396160, 7 pages
Research Article

Patient- and Caregiver-Related Factors Associated with Caregiver Assessed Global Deterioration Scale Scoring in Demented Patients

1Alzheimer Center, Greek Psychogeriatric Association “Nestor”, Athens, Greece
2Medical School, National and Kapodistrian University of Athens, Athens, Greece
3Faculty of Medicine, Comenius University, Bratislava, Slovakia
41st Department of Psychiatry, Aeiginition Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece

Correspondence should be addressed to Antonios A. Mougias; moc.liamg@rotsen.saiguom

Received 28 January 2018; Accepted 7 May 2018; Published 4 June 2018

Academic Editor: Moisés E. Bauer

Copyright © 2018 Antonios A. Mougias et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Informant-based rating scales are widely used in dementia but patients’ and caregivers’ features influence the final scoring. We aimed to evaluate the role of patient- and caregiver-related factors in a caregiver rated Global Deterioration Scale (GDS) score in a sample of Greek patients with dementia. Methods. We included 194 patients with dementia and 194 caregivers/family relatives; Mini-Mental State Examination (MMSE); Neuropsychiatric Inventory (NPI); Katz Index of Activities of Daily Living (K-IADL) were administered to (a) patients and Center for Epidemiologic Studies-Depression (CES-D) Scale; Zarit Burden Interview (ZBI) to (b) caregivers. Participants’ demographics and patients’ and caregivers’ characteristics were entered into a 3-block regression analysis. Results. The final model explained 55% of the total variance of the caregiver assessed GDS score. The following variables significantly contributed to the final model: MMSE (β=-0.524); K-IADL (β=-0.264); ZBI (β=0.145). Conclusion. We herein confirm the contribution of patients’ cognitive and functional status and caregivers’ burden in caregiver rated GDS scoring irrespective of demographic-related characteristics.