Table of Contents Author Guidelines Submit a Manuscript
Current Gerontology and Geriatrics Research
Volume 2018, Article ID 9869343, 8 pages
https://doi.org/10.1155/2018/9869343
Research Article

Magnitude of Anemia in Geriatric Population Visiting Outpatient Department at the University of Gondar Referral Hospital, Northwest Ethiopia: Implication for Community-Based Screening

1Department of Hematology and Immunohematology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, 6200 Gondar, Ethiopia
2Department of Medical Laboratory Sciences, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia
3Department of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia
4Department of Clinical Chemistry, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia

Correspondence should be addressed to Mulugeta Melku; moc.liamg@uklem.ategulum

Received 26 July 2017; Accepted 16 December 2017; Published 8 January 2018

Academic Editor: Fulvio Lauretani

Copyright © 2018 Mulugeta Melku et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. WHO, Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System, World Health Organization, Geneva, Switzerland, 2011.
  2. WHO, Worldwide Prevalence of Anaemia 1993-2005, WHO Global Database on Anaemia, Geneva, Switzerland, 2008.
  3. A. T. A. Nakashima, A. C. F. de Moraes, F. Auler, and R. M. Peralta, “Anemia prevalence and its determinants in Brazilian institutionalized elderly,” Nutrition Journal , vol. 28, no. 6, pp. 640–643, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. V. Argento, J. Roylance, B. Skudlarska, N. Dainiak, and Y. Amoateng-Adjepong, “Anemia Prevalence in a Home Visit Geriatric Population,” Journal of the American Medical Directors Association, vol. 9, no. 6, pp. 422–426, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. V. Bach, G. Schruckmayer, I. Sam, G. Kemmler, and R. Stauder, “Prevalence and possible causes of anemia in the elderly: A cross-sectional analysis of a large European university hospital cohort,” Clinical Interventions in Aging, vol. 9, pp. 1187–1196, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. A. M. van Staden and D. J. V. Weich, “Retrospective analysis of the prevalence and causes of anaemia in hospitalised elderly patients,” South African Family Practice, vol. 57, no. 5, pp. 297–299, 2015. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Tettamanti, U. Lucca, F. Gandini et al., “Prevalence, incidence and types of mild anemia in the elderly: the ‘Health and Anemia’population-based study,” Haematologica, vol. 95, no. 11, pp. 1849–1856, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. B. Robinson, “Cost of anemia in the elderly,” Journal of the American Geriatrics Society, vol. 15, no. 3, pp. s14–s17, 2003. View at Google Scholar
  9. W. B. Ershler, K. Chen, E. B. Reyes, and R. Dubois, “Economic burden of patients with anemia in selected diseases,” Value in Health, vol. 8, no. 6, pp. 629–638, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. S.-M. Bang, J.-O. Lee, Y. J. Kim et al., “Anemia and activities of daily living in the Korean urban elderly population: Results from the Korean Longitudinal Study on Health and Aging (KLoSHA),” Annals of Hematology, vol. 92, no. 1, pp. 59–65, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. R. D. M. Bosco, E. P. S. Assis, R. R. Pinheiro, L. C. V. de Queiroz, L. S. M. Pereira, and C. M. F. Antunes, “Anemia and functional capacity in elderly Brazilian hospitalized patients,” Cadernos de Saúde Pública, vol. 29, no. 7, pp. 1322–1332, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Zilinski, R. Zillmann, I. Becker, T. Benzing, R.-J. Schulz, and G. Roehrig, “Prevalence of anemia among elderly inpatients and its association with multidimensional loss of function,” Annals of Hematology, vol. 93, no. 10, pp. 1645–1654, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. G. Röhrig, “Anemia in the frail, elderly patient,” Clinical Interventions in Aging, vol. 11, pp. 319–326, 2016. View at Publisher · View at Google Scholar · View at Scopus
  14. L. Pires Corona, F. C. Drumond Andrade, Y. A. de Oliveira Duarte, and M. L. Lebrao, “The relationship between anemia, hemoglobin concentration and frailty in Brazilian older adults,” The Journal of Nutrition, Health & Aging, vol. 19, no. 9, pp. 935–940, 2015. View at Publisher · View at Google Scholar · View at Scopus
  15. T. Juárez-Cedillo, L. Basurto-Acevedo, S. Vega-García et al., “Prevalence of anemia and its impact on the state of frailty in elderly people living in the community: SADEM study,” Annals of Hematology, vol. 93, no. 12, pp. 2057–2062, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. C. Trevisan, N. Veronese, F. Bolzetta et al., “Low hemoglobin levels and risk of developing depression in the elderly: Results from the prospective PRO.V.A. study,” Journal of Clinical Psychiatry, vol. 77, no. 12, pp. e1549–e1556, 2016. View at Publisher · View at Google Scholar · View at Scopus
  17. C. Trevisan, N. Veronese, F. Bolzetta et al., “Low Hemoglobin Levels and the Onset of Cognitive Impairment in Older People: The PRO.V.A. Study,” Rejuvenation Research, vol. 19, no. 6, pp. 447–455, 2016. View at Publisher · View at Google Scholar · View at Scopus
  18. A. M. Khan, S. Ashizawa, V. Hlebowicz, and D. W. Appel, “Anemia of aging and obstructive sleep apnea,” Sleep and Breathing, vol. 15, no. 1, pp. 29–34, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Migone De Amicis, E. Poggiali, I. Motta et al., “Anemia in elderly hospitalized patients: prevalence and clinical impact,” Internal and Emergency Medicine, vol. 10, no. 5, pp. 581–586, 2015. View at Publisher · View at Google Scholar · View at Scopus
  20. B. F. Culleton, B. J. Manns, J. Zhang, M. Tonelli, S. Klarenbach, and B. R. Hemmelgarn, “Impact of anemia on hospitalization and mortality in older adults,” Blood, vol. 107, no. 10, pp. 3841–3846, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. M. R. J. Tay and Y. Y. Ong, “Prevalence and risk factors of anaemia in older hospitalised patients,” Proceedings of Singapore Healthcare, vol. 20, no. 2, pp. 71–79, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. F. Landi, A. Russo, P. Danese et al., “Anemia status, hemoglobin concentration, and mortality in nursing home older residents,” Journal of the American Medical Directors Association, vol. 8, no. 5, pp. 322–327, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. H. G. Endres, U. Wedding, D. Pittrow, U. Thiem, H. J. Trampisch, and C. Diehm, “Prevalence of anemia in elderly patients in primary care: Impact on 5-year mortality risk and differences between men and women,” Current Medical Research and Opinion, vol. 25, no. 5, pp. 1143–1158, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. D. L. Smith, “Anemia in the elderly,” American Family Physician, vol. 62, no. 7, pp. 1565–1572, 2000. View at Google Scholar
  25. J. M. Guralnik, R. S. Eisenstaedt, L. Ferrucci, H. G. Klein, and R. C. Woodman, “Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia,” Blood, vol. 104, no. 8, pp. 2263–2268, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. E. Andrès, L. Federici, K. Serraj, and G. Kaltenbach, “Update of nutrient-deficiency anemia in elderly patients,” European Journal of Internal Medicine, vol. 19, no. 7, pp. 488–493, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. S. Loikas, P. Koskinen, K. Irjala et al., “Vitamin B12 deficiency in the aged: A Population-Based Study,” Age and Ageing, vol. 36, no. 2, pp. 177–183, 2007. View at Publisher · View at Google Scholar · View at Scopus
  28. M. López-Sierra, S. Calderón, J. Gómez, and L. Pilleux, “Prevalence of anaemia and evaluation of transferrin receptor (sTfR) in the diagnosis of iron deficiency in the hospitalized elderly patients: Anaemia clinical studies in Chile,” Anemia, vol. 2012, Article ID 646201, 2012. View at Publisher · View at Google Scholar · View at Scopus
  29. H. Kaur, S. Piplani, M. Madan, M. Paul, and S. G. Rao, “Prevalence of Anemia and Micronutrient Deficiency in Elderly,” International Journal of Medical and Dental Sciences, vol. 3, no. 1, pp. 296–302, 2015. View at Publisher · View at Google Scholar
  30. WHO, “Definition of an older or elderly person: Proposed Working Definition of an Older Person in Africa for the MDS Project,” WHO Health statistics and health information systems, 2013, http://www.who.int/healthinfo/survey/ageingdefnolder/en/index.html.
  31. S. Sahin, P. T. Tasar, H. Simsek et al., “Prevalence of anemia and malnutrition and their association in elderly nursing home residents,” Aging Clinical and Experimental Research, vol. 28, no. 5, pp. 857–862, 2016. View at Publisher · View at Google Scholar · View at Scopus
  32. V. Sgnaolin, P. Engroff, L. S. Ely et al., “Hematological parameters and prevalence of anemia among free-living elderly in south Brazil,” Revista Brasileira de Hematologia e Hemoterapia, vol. 35, no. 2, pp. 115–118, 2013. View at Publisher · View at Google Scholar · View at Scopus
  33. A. Ramel, P. V. Jonsson, S. Bjornsson, and I. Thorsdottir, “Anemia, nutritional status, and inflammation in hospitalized elderly,” Nutrition Journal , vol. 24, no. 11-12, pp. 1116–1122, 2008. View at Publisher · View at Google Scholar · View at Scopus
  34. A. Dunn, J. Carter, and H. Carter, “Anemia at the end of life: Prevalence, significance, and causes in patients receiving palliative care,” Journal of Pain and Symptom Management, vol. 26, no. 6, pp. 1132–1139, 2003. View at Publisher · View at Google Scholar · View at Scopus
  35. A. Contreras-Manzano, V. de la Cruz, S. Villalpando, R. Rebollar, and T. Shamah-Levy, “Anemia and iron deficiency in Mexican elderly population. Results from the Ensanut 2012,” Salud Pública de México, vol. 57, no. 5, pp. 394–402, 2015. View at Publisher · View at Google Scholar · View at Scopus
  36. C. Beghé, A. Wilson, and W. B. Ershler, “Prevalence and outcomes of anemia in geriatrics: a systematic review of the literature,” American Journal of Medicine, vol. 116, no. 7, supplement 1, pp. 3S–10S, 2004. View at Publisher · View at Google Scholar · View at Scopus
  37. L. Ferrucci, M. Maggio, S. Bandinelli et al., “Low testosterone levels and the risk of anemia in older men and women,” JAMA Internal Medicine, vol. 166, no. 13, pp. 1380–1388, 2006. View at Publisher · View at Google Scholar · View at Scopus
  38. J. J. Carrero, P. Bárány, M. I. Yilmaz et al., “Testosterone deficiency is a cause of anaemia and reduced responsiveness to erythropoiesis-stimulating agents in men with chronic kidney disease,” Nephrology Dialysis Transplantation , vol. 27, no. 2, pp. 709–715, 2012. View at Publisher · View at Google Scholar · View at Scopus
  39. V. W. Henderson, “Aging, estrogens, and episodic memory in women,” Cognitive and Behavioral Neurology, vol. 22, no. 4, pp. 205–214, 2009. View at Publisher · View at Google Scholar · View at Scopus
  40. E. H. Haddad, L. S. Berk, J. D. Kettering, R. W. Hubbard, and W. R. Peters, “Dietary intake and biochemical, hematologic, and immune status of vegans compared with nonvegetarians,” American Journal of Clinical Nutrition, vol. 70, no. 3, pp. 586s–593s, 1999. View at Google Scholar · View at Scopus
  41. J. Woo, T. Kwok, S. C. Ho, A. Sham, and E. Lau, “Nutritional status of elderly Chinese vegetarians,” Age and Ageing, vol. 27, no. 4, pp. 455–461, 1998. View at Publisher · View at Google Scholar · View at Scopus
  42. R. Pawlak, S. E. Lester, and T. Babatunde, “The prevalence of cobalamin deficiency among vegetarians assessed by serum vitamin B12: A review of literature,” European Journal of Clinical Nutrition, vol. 68, no. 5, pp. 541–548, 2014. View at Publisher · View at Google Scholar · View at Scopus
  43. R. Obeid, J. Geisel, H. Schorr, U. Hübner, and W. Herrmann, “The impact of vegetarianism on some haematological parameters,” European Journal of Haematology, vol. 69, no. 5-6, pp. 275–279, 2002. View at Publisher · View at Google Scholar · View at Scopus
  44. K. E. Charlton and D. Rose, “Nutrition among older adults in Africa: The situation at the beginning of the millenium,” Journal of Nutrition, vol. 131, no. 9, pp. 2424S–2428S, 2001. View at Google Scholar · View at Scopus
  45. I. Colombet, J. Pouchot, V. Kronz et al., “Agreement between erythrocyte sedimentation rate and C-reactive protein in hospital practice,” American Journal of Medicine, vol. 123, no. 9, pp. 863.e7–863.e13, 2010. View at Publisher · View at Google Scholar · View at Scopus
  46. A. A. Merchant and C. N. Roy, “Not so benign haematology: Anaemia of the elderly,” British Journal of Haematology, vol. 156, no. 2, pp. 173–185, 2012. View at Publisher · View at Google Scholar · View at Scopus
  47. C. N. Roy, “Anemia of Inflammation,” International Journal of Hematology, vol. 2010, no. 1, pp. 276–280, 2011. View at Publisher · View at Google Scholar