A Low-Noise, Modular, and Versatile Analog Front-End Intended for Processing In Vitro Neuronal Signals Detected by Microelectrode Arrays

Figure 3

(a) Top view of the 60-channel preamplifier board rendering, highlighting the position of the holes for the insertion of miniaturized spring contacts connecting MEA pads and preamplifier inputs and the location of the output connector. (b) Top view of the four layers composing the preamplifier PCB. Red = top layer, with components and ground plane; blue = mid layer 1, with traces for output signals; green = mid layer 2, with traces for output signals and power supply traces; brown = bottom layer, with ground plane. On the right of each layer there are double row connectors for output signals. (c) Top layer of the dual layers filter amplifier PCB, highlighting signal and power supply traces and components (in red) and signal input/output connectors (in green). The bottom layer (not shown) is dedicated to the ground plane. (d) Detail of the disposition of passive components around each quad-OP of the filter amplifier boards. Component names refer to those in Figure 2. G = ground and Cb = bypass capacitors on power supply lines (V+ and V−).

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