A Low-Noise, Modular, and Versatile Analog Front-End Intended for Processing In Vitro Neuronal Signals Detected by Microelectrode Arrays

Table 4

Comparison of noise levels between custom and commercial benchmark equipment.

[μV RMS]	Custom board	Benchmark system
MEA 1	2.08 ± 1.01	1.97 ± 0.71
MEA 2	1.70 ± 0.24	1.88 ± 0.15
MEA 3	2.01 ± 0.34	1.98 ± 0.27

Input-referred RMS noise levels (mean ± std, channels) measured connecting 3 MEA chips filled with phosphate buffered saline to the custom board and to the commercial benchmark recording equipment. Noise levels refer to 300 Hz–3 kHz frequency range and were comparable between the two setups.