A Low-Noise, Modular, and Versatile Analog Front-End Intended for Processing In Vitro Neuronal Signals Detected by Microelectrode Arrays

Table 5

Comparison of main specifications of the proposed system and two commercial products.

Parameter	This work	MEA1060	The Muse System
		(Multi Channel Systems GmbH)	(Axion Biosystems Ltd.)
Gain	1052	1100^**	1200
f −3 dB (low)	315 Hz	300 Hz^*	200^*
f −3 dB (high)	3110 Hz	3000 Hz^*	3000^*
Noise (input referred, max)	804 nV	800 nV	3 μV
Power consumption of MEA surrounding electronics	550 mW	2 W	N.s.
Environment conditions	37°C, RH > 90%	37°C, RH < 60%	37°C, RH < 60%

^*Specifications suggested to acquire spike signals (the bandwidth can be customized according to the user need). ^**Standard value. N.s. = not specified. RH = relative humidity.