Spike Code Flow in Cultured Neuronal Networks

Figure 1

(Upper) Micrograph of cultured hippocampal neurons in a microelectrode array. Black rectangles indicate electrodes. (Lower) Illustration of a vertical section. Each electrode catches spikes from several neurons. We can observe spike trains containing code such as “1011.” Each bit (“1” or “0”) is considered from different neuron for short time length (short bit width) code, since it takes more time for the same neuron to fire twice than the refractory period.