Hyperbolic Modeling of Subthalamic Nucleus Cells to Investigate the Effect of Dopamine Depletion

Table 5

Exact parameter set to generate spiking patterns of Figure 2 based on the proposed hyperbolic model.

						(A)
Tonic spike	75000	950	16	0.021	0.2	Constant at 14
Tonic burst	75000	1000	16	0.02	0.24	Constant at 15
Phasic spike	75000	1000	16	0.02	0.25	Constant at 0.5
Phasic burst	75000	980	16.6	0.02	0.26	Constant at 1
Rebound spike	75000	1000	16	0.03	0.25	Single pulse with peak of −15
Rebound burst	74000	960	15	0.03	0.2	Single pulse with peak of −15
Inhibition-induced spike	75000	1000	16	−0.02	−1	Pulse with high peak at 80 and low peak at 75
Inhibition-induced burst	71000	1000	15.7	−0.026	−0.8	Pulse with high peak at 80 and low peak at 72
Phasic and tonic spike	73000	920	16.2	0.02	0.2	Constant at 10
Frequency adaptation	75000	1000	16	0.01	0.2	Constant at 30
Spike latency	74000	1000	16.1	0.02	0.18	Single pulse with peak of 7
Depolarized spike	75000	9500	16	1	0.2	Single pulse with peak of 20
Threshold variability	75000	1000	15.3	0.032	0.25	Consecutive pulses with peak at 1
Bistable spike	75000	950	16	0.1	0.26	Consecutive pulses with peak at 1.24