An Efficient Combination among sMRI, CSF, Cognitive Score, and APOE ε4 Biomarkers for Classification of AD and MCI Using Extreme Learning Machine

Table 3

10-fold cross-validated classification performance for AD vs. HC.

Features measure	ELM				SVM-RBF			SVM-linear
	ACC%	SEN%	SPE%	AUC	ACC%	SEN%	SPE%	ACC%	SEN%	SPE%
Cortical thickness	85.13	92.07	85.44	0.86	80.68	85.68	83.81	77.17	83.17	73.81
Surface area	82.30	89.30	91.54	0.85	76.16	86.16	75.14	78.67	87.67	72.62
Volume	87.90	93.87	84.75	0.88	79.29	74.29	78.33	80.00	77.10	63.24
CSF	89.73	96.33	87.38	0.89	79.05	89.05	74.17	75.33	83.33	68.57
APOE + MMSE	86.45	95.13	87.00	0.93	82.03	87.03	84.67	84.16	83.05	78.79
Concatenation (all_features_set)	97.31	98.04	96.28	0.97	91.33	93.33	87.57	93.50	95.5	90.58