An Efficient Combination among sMRI, CSF, Cognitive Score, and APOE ε4 Biomarkers for Classification of AD and MCI Using Extreme Learning Machine

Table 5

10-fold cross-validated classification performance for HC vs. MCI.

Features measure	ELM				SVM-RBF			SVM-linear
	ACC%	SEN%	SPE%	AUC	ACC%	SEN%	SPE%	ACC%	SEN%	SPE%
Cortical thickness	75.40	84.07	67.90	0.83	74.17	80.81	71.23	67.34	73.17	77.93
Surface area	74.15	65.20	83.85	0.84	63.54	67.67	66.47	68.72	74.43	67.35
Volume	77.84	88.41	72.80	0.84	65.47	74.73	68.75	72.83	78.27	65.70
CSF	83.30	73.93	84.02	0.85	73.39	75.25	66.83	75.80	73.38	78.14
APOE + MMSE	79.37	93.25	72.97	0.89	68.29	81.73	76.68	70.23	81.24	78.05
Concatenation (all_features_set)	91.72	91.23	99.13	0.93	81.70	83.68	87.49	85.65	78.54	89.26