Prediction of Cognitive Decline in Temporal Lobe Epilepsy and Mild Cognitive Impairment by EEG, MRI, and Neuropsychology

Figure 4

MRI regions selected for prediction of divided attention decline. For the prediction of divided attention decline, wavelet MRI features were selected from the following regions: insula left, corpus callosum, third ventricle, precentral gyrus left, straight gyrus right, anterior orbital gyrus right, bilateral inferior frontal gyrus, bilateral superior frontal gyrus, postcentral gyrus right, superior parietal gyrus right, lingual gyrus right, cuneus right, bilateral medial orbital gyrus, bilateral lateral orbital gyrus, posterior orbital gyrus left, bilateral substantia nigra, bilateral subgenual frontal cortex, bilateral subcallosal area, bilateral pre-subgenual frontal cortex, and bilateral superior temporal gyrus anterior part. For the prediction of divided attention decline by structural MRI volumetry, the following regions were selected: parahippocampal and ambient gyrus right, brainstem excluding substantia nigra, bilateral posterior cingulate gyrus, middle frontal gyrus left, inferolateral remainder parietal lobe left, nucleus accumbens right, thalamus right, lateral ventricle including temporal horn right, lateral ventricle temporal horn left, straight gyrus left, anterior orbital gyrus right, inferior frontal gyrus left, postcentral gyrus left, superior parietal gyrus right, medial orbital gyrus right, bilateral lateral orbital gyrus, posterior orbital gyrus left, bilateral subgenual frontal cortex, subcallosal area right, and bilateral superior temporal gyrus anterior part.