[Retracted] LncXIST Facilitates Iron Overload and Iron Overload-Induced Islet Beta Cell Injury in Type 2 Diabetes through miR-130a-3p/ALK2 Axis

Figure 3

XIST directly binds to and regulates the expression of miR-130a-3p. (a) The predicted binding sites of miR-130a-3p to XIST sequence using StarBase. (b) The relative luciferase of HEK 923 cells was transfected with miR-130a-3p mimics and luciferase constructs of wild-type (WT) or mutated-type (MUT) XIST-UTR. (c) Overexpression of XIST decreased miR-130a-3p expression. (d) The expression level of miR-130a-3p in tissues of rat. (e) The expression level of miR-130a-3p in INS-1 cells.  < 0.01.

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