Computational Intelligence and Neuroscience

Research Article

Using CNN Saliency Maps and EEG Modulation Spectra for Improved and More Interpretable Machine Learning-Based Alzheimer’s Disease Diagnosis

Top 24 features selected using the experiment 1 settings.


Rankings	N vs. AD1 vs. AD2	N vs. AD	N vs. AD1	AD1 vs. AD2	N vs. AD2

1	R3-C4₁	R2-F7₂	R2-F7₃	R2-Oz₄	R3-C4₅
2	R3-P3₁	R3-F7₂	R1oR2-F7₃	R2-Fz₄	R3-P3₅
3	R3-Fz₁	R2-C4₂	R1oR3-Oz₃	R2-F4₄	R3-C3₅
4	R3-Oz₁	R1-C4₂	R1oR3-Pz₃	R2-P3₄	R3-F3₅
5	R3-F3₁	R3-C4₂	R1oR3-O2₃	R3oR2-C3₄	R3-P4₅
6	R3-C3₁	R1-F7₂	R2-C4₃	R2-F3₄	R3-T4₅
7	R3-F4₁	R2-T4₂	R1oR3-O1₃	R4oR2-C3₄	R2-C4₅
8	R3-P4₁	R4-C4₂	R2-T3₃	R2-C3₄	R3-F4₅
9	R3-Cz₁	R2-F3₂	R1oR2-T4₃	R2-O2₄	R2-F3₅
10	R3-T4₁	R2-T3₂	R1oR2-C4₃	R2-Pz₄	R3-Oz₅
11	R3-O1₁	R3-T4₂	R1oR2-C3₃	R5oR2-C3₄	R3-Fz₅
12	R3-O2₁	R3-F3₂	R1oR2-F3₃	R2-O1₄	R2-P3₅
13	R3-Pz₁	R2-T6₂	R2-T6₃	R3oR1-C3₄	R2-T4₅
14	R2-C4₁	R1-T4₂	R3-F7₃	R2-Cz₄	R1-F3₅
15	R1-F7₁	R2oR3-F8₂	R1oR2-T3₃	R1oR2-C3₄	R3-T5₅
16	R2-F3₁	R3-T3₂	R2-T4₃	R1oR2-F7₄	R3-O1₅
17	R2-fz₁	R4-F7₂	R1oR3-Fp1₃	R5oR3-C3₄	R1-C4₅
18	R1-C4₁	R2-C3₂	R1oR2-T6₃	R2-P4₄	R2-Fz₅
19	R1-F3₁	R4-T4₂	R1oR3-P4₃	R3oR2-F7₄	R3-T6₅
20	R2-P3₁	R2oR3-F7₂	R3oR2-T3₃	R4oR1-C3₄	R2-C3₅
21	R1-T4₁	R1-F3₂	R3oR2-F7₃	R5oR4-C3₄	R3-Cz₅
22	R2-T4₁	R3-T6₂	R1oR2-Fp1₃	R2-C4₄	R1-T4₅
23	R3-T5₁	R2-P3₂	R1oR2-T5₃	R1-Oz₄	R2-F4₅
24	R2-F4₁	R2oR3-T4₂	R1oR2-F8₃	R5oR3-T5₄	R2-P4₅

Number of features per brain region—experiment 1 settings
Frontal	8	9	8	5	7
Central	5	5	3	11	6
Temporal	4	9	8	1	5
Parietal	4	1	2	3	4
Occipital	3	0	3	4	2