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Canadian Journal of Gastroenterology
Volume 3, Issue 4, Pages 141-144
Brief Communication

Psudoxanthoma elasticum: An Unusual Case of Gastrointestinal Bleeding

Deborah J. Cook, Samih S. Salama, and Robert J. Tuttle

Departments of Medicine, Pathology and Radiology, St Joseph’s Hospital, McMaster University, Hamilton, Ontario, Canada

Received 1 December 1988; Accepted 8 May 1989

Copyright © 1989 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Pseudoxanchoma elasticum (PXE) is an inherited disorder of connective tissue, characterized by calcification and degeneration of elastin. Clinical manifestations of PXE are protean, with skin, eyes and arteries being most commonly involved. Although often a benign condition, gastrointestinal hemorrhage is a potentially fatal complication. An unusual case of gastrointestinal hemorrhage in a patient with PXE is described and the pathophysiology, clinical presentation and complications of this rare condition are reviewed.