Abstract
Diagnostic upper gastrointestinal endoscopy has increased the frequency with which duodenal lipomas are encountered in clinical practice. Although the smaller lesions are usually incidental endoscopic findings unrelated to symptoms, an accurate diagnosis depends upon biopsy and histological assessment Larger lesions may bleed or obstruct. The authors present two cases: one lipoma was found incidentally during the investigation of an esophageal motility disorder; the other larger one presented as a mass lesion in a patient with upper gastrointestinal bleeding. Pathological findings suggested that the lipoma was the cause of the bleeding. Management is briefly discussed.