Table of Contents Author Guidelines Submit a Manuscript
Canadian Journal of Gastroenterology
Volume 5, Issue 2, Pages 71-74
Brief Communication

Signet-Ring Cell Carcinoma of the Colon Radiologically Stimulating Crohn’s Colitis

Wing C Peter Kwan and Hugh J Freeman

University Hospital and University of British Columbia, Vancouver, British Columbia, Canada

Received 30 November 1990; Accepted 11 March 1991

Copyright © 1991 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 35-year-old male with abdominal pain and weight loss was referred with a diagnosis of Crohn’s colitis. Subsequent colonoscopic examination and laparotomy revealed diffuse infiltration of the colonic wall with a primary signet-ring cell carcinoma and widespread metastases. The poor prognosis of this lesion appears to reflect difficulty in early diagnosis as well as the unusual cell biological features of this highly invasive histological variety of colon carcinoma.