Canadian Journal of Gastroenterology and Hepatology

Canadian Journal of Gastroenterology and Hepatology / 1994 / Article

Brief Communication | Open Access

Volume 8 |Article ID 150426 |

Hugh J Freeman, "Celiac Disease Assocaited with Primary Biliary Cirrhosis in a Coast Salish Native", Canadian Journal of Gastroenterology and Hepatology, vol. 8, Article ID 150426, 3 pages, 1994.

Celiac Disease Assocaited with Primary Biliary Cirrhosis in a Coast Salish Native

Received09 Jul 1993
Accepted30 Jul 1993


A 41-year-old Coast Salish female was initially diagnosed with typical features of classical adult celiac disease. Clinical and pathological features of primary biliary cirrhosis were also present, along with a familial history of insulin-dependent diabetes. Later, childhood celiac disease was detected in a male first-degree relative with diabetes. These patients are the first reported natives in Canada with celiac disease, a disorder believed to be genetically based but dependent on environmental factors for its clinical expression. The recognition of a ‘new’ disease in the setting of an aboriginal population may reflect geographical and climatic factors that permitted subsistence of this culturally complex food-gathering society up until most recent historical times, followed by adaptation of this society to European-based agricultural methods, particularly wheat cultivation.

Copyright © 1994 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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