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Canadian Journal of Gastroenterology
Volume 8, Issue 4, Pages 253-256
Brief Communications

Childhood Peutz-Jeghers Syndrome: Diversity of Clinical Features and Complications, and Literature Review

Mark R Oliver, R Brent Scott, Robin C Eccles, Cynthia Trevenen, Jonathon B Meddings, and Steven R Martin

Departments of Medicine, Pathology, Pediatrics and Surgery, Alberta Children’s Hospital and University of Calgary, Calgary, Alberta, Canada

Received 7 February 1994; Accepted 8 February 1994

Copyright © 1994 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This case report of a six-year-old child with Peutz-Jeghers syndrome illustrates the potential diversity of presenting gastrointestinal symptoms and signs including hematemesis, obstruction and recurrent intussusception. Endoscopy was useful in assessment, while endoscopic polypectomy and surgical resection were both necessary for management. The literature is reviewed and the possible role that this syndrome may have in the development of both gastrointestinal and nongastrointestinal tumours is highlighted.