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Canadian Journal of Gastroenterology
Volume 8, Issue 2, Pages 92-96
Case Record

Granular Cell Tumour of the Bile Duct in Association with Intrahepatic Bile Duct Adenomas

F Schweiger, J Radhi, FW Coop, and RW Murphy

Departments of Internal Medicine (Gastroenterology Division), Pathology, Medical Imaging and Surgery, The Moncton Hospital, Moncton, New Brunswick, Canada

Received 26 July 1993; Accepted 16 August 1993

Copyright © 1994 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Granular cell tumour of the extrahepatic biliary tract is a rare benign lesion likely of neurogenic origin. Review of the previously reported cases indicates that almost all patients are female, and the majority is Black. Symptoms usually are those of biliary obstruction or cholecystitis. Surgical resection of the tumour is curative. Intrahepatic bile duct adenoma is another rare benign biliary neoplasm that does not manifest clinically but can be confused with metastatic carcinoma, cholangiocarcinoma or other focal liver lesions at laparotomy or autopsy. The authors report the case of an asymptomatic Caucasian woman with biochemical evidence of liver disease who had a granular cell tumour of the bile duct as well as several intrahepatic bile duct adenomas.