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Canadian Journal of Gastroenterology
Volume 8, Issue 5, Pages 308-312

A Potential Prognostic Indicator of Fulminant Hepatic Failure: A Valuable Adjunct in Preliver Transplant Assessment

B Yacyshyn,1 CM Cheung,1 D Gordon Malkin,2 and SC Pappas3

1Departments of Clinical Biochemistry and Medicine, Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada
2Sunnybrook Medical Centre, Toronto, Ontario, Canada
3Department of Transplantation, Methodist Hospital, Indianapolis, Indiana, USA

Received 14 December 1993; Accepted 27 April 1994

Copyright © 1994 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The use of thyroid function tests as a method of monitoring patients with fulminant hepatic failure has been previously proposed. The use of these indices in two cases with fulminant hepatic failure are described. Both patients had simultaneous ingestion of hepatotoxic mushroom (amanita virosa). Their parallel clinical courses and recovery without liver transplantation is described, outlining the potential long term cost-savings achievable by such tests in the selection of patients for liver transplantation and the need for further study of these indices for this application.