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Canadian Journal of Gastroenterology
Volume 9, Issue 2, Pages 78-80
Brief Communication – Hepatology

Wilson’s Disease in an Elderly Patient

Maziar Badii, Henry Wong, Urs P Steinbrecher, and Hugh J Freeman

Department of Medicine (Gastroenterology), University of British Columbia, Vancouver, British Columbia, Canada

Received 31 May 1994; Accepted 15 August 1994

Copyright © 1995 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 65-year-old man with Fanconi’s syndrome was investigated for the cause of chronic liver disease. Wilson’s disease was diagnosed based on the detection of bilateral Kayser-Fleischer rings, a low serum ceruloplasmin level, increased urine copper excretion and positive histochemical stains of his liver for copper. This case is unusual because of the patient’s elderly age at the time of diagnosis and the absence of neurological changes due to Wilson’s disease in spite of advanced hepatic disease and the presence of Kayser-Fleischer rings. Even in the elderly patient, Wilson’s disease should be considered a possible cause of chronic liver disease.