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Canadian Journal of Gastroenterology
Volume 11, Issue 6, Pages 507-511
Original Article

Pilot Study of Ofloxacin and Interferon-Alpha Combination Therapy for Chronic Hepatitis C without Sustained Response to Initial Interferon Therapy

Masafumi Komatsu, Tohru Ishii, Tsuyoshi Ono, Takao Hoshino, Tomoyuki Kuramitsu, Takashi Goto, Tomoo Fujii, Itaru Toyoshima, Mitsuro Chiba, and Osamu Masamune

First Department of Internal Medicine, Akita University School of Medicine, Hondo, Akita City, Japan

Received 29 January 1997; Accepted 28 May 1997

Copyright © 1997 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [9 citations]

The following is the list of published articles that have cited the current article.

  • Francesco Negro, Pierre-Jean Male, Luc Perrin, Emiliano Gistra, and Antoine Hadengue, “Treatment of chronic hepatitis C with α-interferon plus ofloxacin in patients not responding to α-interferon alone,” Journal of Hepatology, vol. 29, no. 3, pp. 369–374, 1998. View at Publisher · View at Google Scholar
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  • Sk Sarin, “What should we advise about adjunctive therapies, including herbal medicines, for hepatitis C?,” Journal of Gastroenterology and Hepatology, vol. 15, no. 5(Suppl.), pp. E164–E171, 2000. View at Publisher · View at Google Scholar
  • Seng-Lai Tan, Arnim Pause, Yuguang Shi, and Nahum Sonenberg, “Hepatitis C therapeutics: current status and emerging strategies,” Nature Reviews Drug Discovery, vol. 1, no. 11, pp. 867–881, 2002. View at Publisher · View at Google Scholar
  • Kojima, Kaita, Hawkins, Uhanova, and Minuk, “Use of fluoroquinolones in patients with chronic hepatitis C virus-induced liver failure,” Antimicrobial Agents and Chemotherapy, vol. 46, no. 10, pp. 3280–3282, 2002. View at Publisher · View at Google Scholar
  • Cristina Parolin, Sara Richter, Manlio Palumbo, and Giorgio Palù, “Antiviral properties of quinolone-based drugs,” Current Drug Targets - Infectious Disorders, vol. 4, no. 2, pp. 111–116, 2004. View at Publisher · View at Google Scholar
  • şahin Çoban, Bilge Ceydilek, Fuat Ekiz, Esra Erden, and İrfan Soykan, “Levofloxacin-Induced Acute Fulminant Hepatic Failure in a Patient with Chronic Hepatitis B Infection,” Annals of Pharmacotherapy, vol. 39, no. 10, pp. 1737–1740, 2005. View at Publisher · View at Google Scholar
  • Christine Hanssen Rinaldo, and Hans H. Hirsch, “Antivirals for the treatment of polyomavirus BK replication,” Expert Review of Anti-Infective Therapy, vol. 5, no. 1, pp. 105–115, 2007. View at Publisher · View at Google Scholar
  • Sammer Siddiqui, Shahana U. Kazmi, Irfan A. Khan, Sadiq Rehmani, and Syed H. Ali, “Fluoroquinolones inhibit HCV by targeting its helicase,” Antiviral Therapy, vol. 17, no. 3, pp. 467–476, 2012. View at Publisher · View at Google Scholar