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Canadian Journal of Gastroenterology
Volume 15, Issue 6, Pages 405-409
Brief Communication

Intestinal Carcinoid Tumours in a Father and Daughter

Tuya Pal,1 Alexander Liede,1 Margot Mitchell,1 Alain Calender,2 and Steven A Narod1

1Centre for Research in Women’s Health, Sunnybrook and Women’s College Health Sciences Centre, Toronto, Ontario, Canada
2Genetic Unit, Pavillon E, Hôpital Edouard Herriot, Place d’Arsonval, Lyon, , France

Received 16 May 2000; Accepted 8 August 2000

Copyright © 2001 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Familial cases of carcinoid tumours that are not associated with any known syndrome or disease are extremely rare. All cases reported in the world literature have involved carcinoid tumours of the gastrointestinal tract. Two cases of carcinoid tumours of the small intestine in a father and daughter are presented. Laboratory analyses did not support the hypothesis that the occurrence of carcinoid tumours in this family is a variant of the multiple endocrine neoplasia type 1 syndrome. A review of the literature on familial occurrence of intestinal carcinoid tumours in the absence of any other known carcinoid tumour-predisposing genetic syndrome is provided.