Brief Communication | Open Access
Jennifer L Shin, Geoffrey W Gardiner, Wayne Deitel, Gabor Kandel, "Does Whipworm Increase the Pathogenicity of Campylobacter jejuni? A Clinical Correlate of an Experimental Observation", Canadian Journal of Gastroenterology and Hepatology, vol. 18, Article ID 298064, 3 pages, 2004. https://doi.org/10.1155/2004/298064
Does Whipworm Increase the Pathogenicity of Campylobacter jejuni? A Clinical Correlate of an Experimental Observation
Campylobacter jejuni is a leading cause of acute diarrhea worldwide, usually mild and self-limiting. No adequate hypothesis has yet been formulated to explain why in an otherwise healthy host this infection is occasionally severe. In a pig model, C jejuni has been shown to be pathogenic only in the presence of swine whipworm. A human case of life-threatening C jejuni colitis leading to toxic megacolon and acute renal failure, associated with concomitant whipworm (Trichuris suis) ova in the feces, is reported. The potential of T suis to potentiate C jejuni in humans deserves further study.
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