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Canadian Journal of Gastroenterology
Volume 21, Issue 6, Pages 363-366
http://dx.doi.org/10.1155/2007/951526
Original Article

Application of the Montreal Classification for Crohn’s Disease to a Single Clinician Database of 1015 Patients

Hugh J Freeman

Department of Medicine (Gastroenterology), University of British Columbia, Vancouver, British Columbia, Canada

Received 28 March 2006; Accepted 19 July 2006

Copyright © 2007 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Crohn’s disease involves different gastrointestinal sites and may be characterized by high rates of strictures and penetrating complications. The present study applied the newly described Montreal schema of classification to a large, prospectively accumulated clinical database. In addition, age dependence was evaluated at diagnosis, with regard to disease location and disease behaviour. There were 1015 consecutively evaluated patients (449 male and 566 female). Disease was most often localized in the ileocolon and was usually complex with stricture formation or penetrating complications. For both sexes, with increasing age at diagnosis, Crohn’s disease was less extensive, more often localized in the colon alone and characterized by less complex disease behaviour, especially with less penetrating disease complications. Using the Montreal classification for Crohn’s disease, these results define the clinical features in a large, single clinician database and demonstrate age dependence in the phenotypic clinical expression of Crohn’s disease.