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Canadian Journal of Gastroenterology
Volume 22, Issue 5, Pages 457-459
Current Endoscopic Practices – The Experts Speak

Propofol Use for Sedation during Endoscopy in Adults: A Canadian Association of Gastroenterology Position Statement

Michael F Byrne,1 Naoki Chiba,2 Harminder Singh,3 Daniel C Sadowski,4 and for the Clinical Affairs Committee of the Canadian Association of Gastroenterology

1University of British Columbia, Vancouver, British Columbia, Canada
2McMaster University, Hamilton, Ontario, Canada
3University of Manitoba, Winnipeg, Manitoba, Canada
4University of Alberta, Edmonton, Alberta, Canada

Received 27 February 2008; Accepted 2 March 2008

Copyright © 2008 Canadian Association of Gastroenterology. This open-access article is distributed under the terms of the Creative Commons Attribution Non-Commercial License (CC BY-NC) (, which permits reuse, distribution, and reproduction of the article, provided that the original work is properly cited and the reuse is restricted to noncommercial purposes.


Over the past decade, multiple clinical reports have demonstrated that the use of propofol sedation for gastrointestinal endoscopy by gastroenterologists and trained endoscopy nurses is safe and effective in appropriately selected patients. Proposed benefits of propofol sedation include rapid onset of action, improved patient comfort and rapid clearance, as well as prompt recovery and discharge from the endoscopy unit. As a result of medical evidence, a number of international professional societies have endorsed the use of propofol in gastrointestinal endoscopy. In Canada, no formal guidelines currently exist. In the present article, the Clinical Affairs Committee of the Canadian Association of Gastroenterology presents a position statement, incorporating updated information on the use of propofol sedation for endoscopy in adult patients.