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Canadian Journal of Gastroenterology
Volume 22, Issue 8, Pages 686-688

Microscopic Colitis: An Approach to Treatment

Nilesh Chande

Division of Gastroenterology, The University of Western Ontario, London, Ontario, Canada

Received 24 May 2008; Accepted 24 May 2008

Copyright © 2008 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Microscopic colitis – including collagenous colitis and lymphocytic colitis – causes chronic watery diarrhea, usually in middle-aged or elderly patients. There is an association with celiac disease and certain medications. Medical treatment includes various antidiarrheal agents, mesalamine, corticosteroids and immunosuppressant drugs. Rarely, patients require surgery for refractory disease. An evidence-based and practical approach to treatment should optimize the treatment response while minimizing potential adverse events.