Thiopurines in the Management of Crohn’s Disease: Safety and Efficacy Profile in Patients with Normal TPMT Activity—A Retrospective Study

Table 2

Side effect profile of thiopurine therapy over study period.

	Full dose ()	Low dose ()	value
Patients with complications	42 (49%)	24 (49%)	1.000
GI intolerance	16 (19%)	7 (14%)	0.636
Hepatitis	5 (6%)	1 (2%)	0.415
Pancreatitis	2 (2%)	5 (10%)	0.0992
Myelosuppression	8 (9%)	5 (10%)	1.000
Others	12 (14%)	6 (12%)	1.000
Discontinued treatment	24 (28%)	19 (39%)	0.250