Table of Contents Author Guidelines Submit a Manuscript
Canadian Journal of Gastroenterology and Hepatology
Volume 2016, Article ID 1329532, 7 pages
http://dx.doi.org/10.1155/2016/1329532
Research Article

Validation of the Model of End-Stage Liver Disease for Liver Transplant Allocation in Alberta: Implications for Future Directions in Canada

1Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, AB, Canada T2N 4Z6
2Alberta Liver Transplant Program, University of Alberta, Edmonton, AB, Canada
3Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada

Received 10 February 2015; Accepted 27 April 2015

Copyright © 2016 Kelly W. Burak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. P. Myers, M. Krajden, M. Bilodeau et al., “Burden of disease and cost of chronic hepatitis C virus infection in Canada,” Canadian Journal of Gastroenterology and Hepatology, vol. 28, no. 5, pp. 243–250, 2014. View at Google Scholar · View at Scopus
  2. M. R. Lucey, K. A. Brown, G. T. Everson et al., “Minimal criteria for placement of adults on the liver transplant waiting list: a report of a national conference organized by the American Society of Transplant Physicians and the American Association for the Study of Liver Diseases,” Liver Transplantation and Surgery, vol. 3, no. 6, pp. 628–637, 1997. View at Publisher · View at Google Scholar · View at Scopus
  3. R. B. Freeman Jr., R. H. Wiesner, A. Harper et al., “The new liver allocation system: moving toward evidence-based transplantation policy,” Liver Transplantation, vol. 8, no. 9, pp. 851–858, 2002. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Malinchoc, P. S. Kamath, F. D. Gordon, C. J. Peine, J. Rank, and P. C. J. Ter Borg, “A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts,” Hepatology, vol. 31, no. 4, pp. 864–871, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. P. S. Kamath, R. H. Wiesner, M. Malinchoc et al., “A model to predict survival in patients with end-stage liver disease,” Hepatology, vol. 33, no. 2, pp. 464–470, 2001. View at Publisher · View at Google Scholar · View at Scopus
  6. F. Botta, E. Giannini, P. Romagnoli et al., “MELD scoring system is useful for predicting prognosis in patients with liver cirrhosis and is correlated with residual liver function: a European study,” Gut, vol. 52, no. 1, pp. 134–139, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. R. H. Wiesner, S. V. McDiarmid, P. S. Kamath et al., “MELD and PELD: application of survival models to liver allocation,” Liver Transplantation, vol. 7, no. 7, pp. 567–580, 2001. View at Publisher · View at Google Scholar · View at Scopus
  8. R. Wiesner, E. Edwards, R. Freeman et al., “Model for end-stage liver disease (MELD) and allocation of donor livers,” Gastroenterology, vol. 124, no. 1, pp. 91–96, 2003. View at Publisher · View at Google Scholar
  9. R. B. Freeman Jr., “MELD/PELD: one year later,” Transplantation Proceedings, vol. 35, no. 7, pp. 2425–2427, 2003. View at Publisher · View at Google Scholar · View at Scopus
  10. K. M. Olthoff, R. S. Brown Jr., F. L. Delmonico et al., “Summary report of a national conference: evolving concepts in liver allocation in the MELD and PELD era,” Liver Transplantation, vol. 10, supplement 2, pp. A6–A22, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. J. A. Hanley and B. J. McNeil, “The meaning and use of the area under a receiver operating characteristic (ROC) curve,” Radiology, vol. 143, no. 1, pp. 29–36, 1982. View at Publisher · View at Google Scholar · View at Scopus
  12. W. K. Kremers, M. van Ijperen, W. R. Kim et al., “MELD score as a predictor of pretransplant and posttransplant survival in OPTN/UNOS status 1 patients,” Hepatology, vol. 39, no. 3, pp. 764–769, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. W. R. Kim, S. W. Biggins, W. K. Kremers et al., “Hyponatremia and mortality among patients on the liver-transplant waiting list,” New England Journal of Medicine, vol. 359, no. 10, pp. 1018–1026, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. M. D. Leise, W. R. Kim, W. K. Kremers, J. J. Larson, J. T. Benson, and T. M. Therneau, “A revised model for end-stage liver disease optimizes prediction of mortality among patients awaiting liver transplantation,” Gastroenterology, vol. 140, no. 7, pp. 1952–1960, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. C. Toso, S. Asthana, D. L. Bigam, A. M. J. Shapiro, and N. M. Kneteman, “Reassessing selection criteria prior to liver transplantation for hepatocellular carcinoma utilizing the scientific registry of transplant recipients database,” Hepatology, vol. 49, no. 3, pp. 832–838, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. K. W. Burak and N. M. Kneteman, “An evidence-based multidisciplinary approach to the management of hepatocellular carcinoma (HCC): the Alberta HCC algorithm,” Canadian Journal of Gastroenterology, vol. 24, no. 11, pp. 643–650, 2010. View at Google Scholar · View at Scopus
  17. M. Bhat, P. Ghali, A. Roy et al., “A novel MELD exception point system for hepatocellular carcinoma promotes equitable liver allocation,” Hepatology, vol. 60, no. 1, supplement, article 199A, 2014. View at Google Scholar